（五年内） 1、合肥工业大学人才引进启动基金, 2017.12-2022.12, 主持. 2、生命分析化学国家重点实验室开放基金, 2018.3-2020.3 (NO. SKLACLS1812), 主持. 3、国家自然科学基金面上项目，2017.1-2020.12（NO. 81671757）, 参研. 4、国家自然科学基金青年科学基金项目，2016.1-2018.12（NO. 21632008）, 参研. 5、国家自然科学基金面上项目，2015.1-2018.12 （NO. 21475014）, 参研.

1.Yizhong Shen, Adam J. Shuhendler, Deju Ye*, Jing-Juan Xu, Hong-Yuan Chen*. Two-photon excitation nanoparticles for photodynamic therapy. Chem. Soc. Rev., 2016, 45, 6725-6741. (Inside cover) 2.Yizhong Shen, Yidan Sun, Runqi Yan, Deju Ye*, Jing-Juan Xu*, Hong-Yuan Chen*. Rational engineering of semiconductor QDs enabling remarkable 1O2 production for tumor-targeted photodynamic therapy. Biomaterials, 2017, 148, 31-40. 3.Yizhong Shen, Qian Tian, Yidan Sun, Jing-Juan Xu, Deju Ye*, Hong-Yuan Chen*. ATP-Activatable photosensitizer enables dual fluorescence imaging and targeted photodynamic therapy of tumor. Anal. Chem., 2017, 89, 13610–13617. 4.Yizhong Shen, Nan Zhang, Yidan Sun, Wei-Wei Zhao, Jing-Juan Xu, Deju Ye*, Hong-Yuan Chen*. Activatable QD-based near-infrared fluorescence probe for sensitive detection and imaging of DNA. ACS Appl. Mater. Interfaces, 2017, 9, 25107-25113. 5.Qiu-Mei Feng+, Yizhong Shen+, Mei-Xing Li+, Zhuo-Lei Zhang, Wei Zhao*, Jing-Juan Xu*, Hong-Yuan Chen. Dual-wavelength electrochemiluminescence ratiometry based on resonance energy transfer between Au nanoparticles functionalized g-C3N4 nanosheet and Ru(bpy)32+ for microRNA detection. Anal. Chem., 2016, 88, 937-944. (+Equal contributions) 6.Yizhong Shen, Shaopu Liu, Ling Kong, Xuanping Tan, Youqiu He* and Jidong Yang*. Detection of DNA using an “off-on” switch of a regenerating biosensor based on an electron transfer mechanism from glutathione-capped CdTe quantum dots to nile blue. Analyst, 2014, 139, 5858-5867. 7.Yizhong Shen, Shaopu Liu, Jidong Yang, Linlin Wang, Xuanping Tan, Youqiu He*. A novel and sensitive turn-on fluorescent biosensor for the DNA detection using Sm3+-modulated glutathione-capped CdTe quantum dots. Sens. Actuators B Chem., 2014, 199, 389-397. 8.Yizhong Shen, Shaopu Liu, Lei Wang, Pengfei Yin, Dan Li, Youqiu He*. Characterization of the interaction of a mono-6-thio-b-cyclodextrin-capped CdTe quantum dots-methylene blue/methylene green system with herring sperm DNA using a spectroscopic approach. Luminescence, 2014, 29, 884-892. 9.Yizhong Shen, Shaopu Liu, Youqiu He*. Fluorescence quenching investigation on the interaction of glutathione-CdTe/CdS quantum dots with sanguinarine and its analytical application. Luminescence, 2014, 29, 176-182. 10.Yizhong Shen, Shaopu Liu, Ling Kong, Dan Li, Youqiu He*. Sensitive detection of polymyxin B sulfate at the nanogram level using enhanced resonance scattering signals and decreased fluorescence signals with thioglycolic acid capped CdTe/CdS quantum dots as probe. Sens. Actuators B Chem., 2013, 188, 555-563. 11.Yizhong Shen, Shaopu Liu, Jian Wang, Dan Li, Xiaodan Wang, Youqiu He*. A sensitive assay of chelerythrine using fluorescence quenching approach with glutathione capped CdTe/CdS quantum dots as probe. Anal. Methods, 2013, 5, 5309-5316. 12.Yizhong Shen, Shaopu Liu, Jian Wang, Dan Li, Youqiu He*. Determination of ellagic acid by fluorescence quenching method with glutathione capped CdTe quantum dots as probe. Anal. Methods, 2013, 5, 3228-3234. 13.Yizhong Shen, Shaopu Liu, Zhengqing Liu, Youqiu He*. Sensitive detection of luteolin using thioglycolic acid-capped cadmium telluride/cadmium sulphide quantum dots as the fluorescent probe. Spectrosc. Lett. 2013, 46, 483-492. 14.Yizhong Shen, Shaopu Liu, Peifei Yin, Youqiu He*. Interaction of Herring Sperm DNA with Lomefloxacin Hydrochloride-Cu(II) Based on Changes in the Fluorescence Intensity of GSH-CdTe/CdS Quantum Dots. Chem. J. Chinese U., 2013, 34, 1360-1367.